* This laboratory test requires a consultation before ordering. BOOK HERE.
 
Method - Blood draw
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Items tested
S-Adenosyl Methionine (SAMe)
S-Adenosyl Homocysteine (SAH)
SAMe:SAH ratio
5-methyl tetrahydrofolate (5MTHF)
Folinic acid,
Tetrahydrofolate (THF)
 
Understanding Methylation and Why It Matters
Methylation is a natural process in the body where certain nutrients, called methyl donors, attach to DNA, genes, and proteins to keep them active and working properly. Think of it as a “switch and repair system” that helps your body run smoothly at a cellular level.
This process is especially important for supporting:
DNA health – making, maintaining, and repairing your genes
Brain and nervous system function – affecting memory, mood, and neurological health
Immune function – helping the body respond appropriately to threats
 
Why Methylation Matters for Health
Proper methylation helps your body with a wide range of important functions, including:
Detoxification and liver support
Energy production
Reducing inflammation
Making neurotransmitters that influence mood and focus
Managing homocysteine, a compound linked to heart and brain health
Supporting protein function and overall cellular health
 
When methylation doesn’t work as it should, it can contribute to health concerns such as:
Autoimmune conditions (like lupus or multiple sclerosis)
Neurological conditions (such as dementia, seizures, or chronic fatigue syndrome)
Mood disorders (depression, anxiety)
Developmental conditions (autism, ADD, ADHD)
Increased risk of birth defects or certain cancers
 
Supporting methylation through targeted nutrients and lifestyle changes has been linked to:
Improved behavior and focus in ADD/ADHD
Enhanced cognitive function and memory
Faster developmental progress, such as speech improvement in children