* This laboratory test requires a consultation before ordering. BOOK HERE.
 
Method - Buccal swab
 
The MyDNA Detoxification Report looks at how your genes may influence your body’s natural ability to process and eliminate toxins. This can help identify areas where your detoxification pathways may be working more slowly or less efficiently, allowing for more personalised nutrition and lifestyle recommendations.
 
Detoxification is a normal process the body uses every day to break down and remove substances such as:
Environmental chemicals
Pollution and toxins
Medications
Hormones
Alcohol
By products created during normal metabolism
 
The liver is one of the main organs involved in detoxification, and this process occurs in two important stages.
 
Phase I Detoxification
Phase I helps break down toxins into intermediate compounds so they can be processed further. This stage is largely controlled by a group of enzymes called cytochrome P450 enzymes.
 
Genes assessed in Phase I include:
CYP1A1
CYP1A2
CYP1B1
CYP2A6
CYP2C9
CYP2C19
CYP2D6
CYP3A4
 
Phase II Detoxification
Phase II helps package and neutralise these compounds so they can be safely removed from the body through urine or bile.
 
Genes assessed in Phase II include:
COMT
NAT1
NAT2
GSTM1
GSTP1
SOD2
 
Variations in these genes may influence how efficiently your body processes toxins, medications, hormones and oxidative stress. Some people may detoxify substances more slowly or more rapidly than others, which can affect sensitivity to chemicals, medication responses and overall toxin load.
 
The report analyses specific genetic markers including:
COMT
CYP1A1 2C
CYP1A2
CYP1B1 6
CYP2C19 17
CYP2C9 2 and 3
CYP2D6 10
CYP3A4 1B
GSTM1
GSTP1
NAT1
NAT2
SOD2
 
The information from this report can help guide personalised recommendations around:
Nutritional support for detoxification pathways
Antioxidant support
Medication metabolism awareness
Reducing environmental toxin exposure
Lifestyle strategies to support liver health and overall wellbeing
 
Testing is performed using advanced genetic technologies to ensure accurate and reliable results.